| Pair Name | Ginsenoside Rg5, Paclitaxel | ||
| Phytochemical Name | Ginsenoside Rg5 (PubChem CID: 11550001 ) | ||
| Anticancer drug Name | Paclitaxel (PubChem CID: 36314 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Ginsenoside Rg5, Paclitaxel | |||
| Disease Info | [ICD-11: 2C77] | Cervical cancer | Investigative | |
| Biological Phenomena | Induction-->Apoptosis | |||
| Gene Regulation | Up-regulation | Expression | BAK1 | hsa578 |
| Up-regulation | Expression | BAX | hsa581 | |
| Up-regulation | Expression | BBC3 | hsa27113 | |
| Down-regulation | Expression | BCL2 | hsa596 | |
| Down-regulation | Expression | BCL-xL | hsa598 | |
| Up-regulation | Expression | BID | hsa637 | |
| Down-regulation | Expression | BIRC3 | hsa330 | |
| Up-regulation | Activity | CASP3 | hsa836 | |
| Up-regulation | Activity | CASP9 | hsa842 | |
| Down-regulation | Expression | MCL1 | hsa4170 | |
| In Vitro Model | HeLa | Human papillomavirus-related cervical adenocarcinoma | Homo sapiens (Human) | CVCL_0030 |
| HeLa/PTX | Papillomavirus-related cervical adenocarcinoma | Homo sapiens (Human) | CVCL_HF87 | |
| Result | Ginsenoside Rg5 Sensitizes Paclitaxel-Resistant Human Cervical-Adeno-Carcinoma Cells to Paclitaxel-And Enhances the Anticancer Effect of Paclitaxel | |||
| No. | Title | Href |
|---|---|---|
| 1 | Ginsenoside Rg5 Sensitizes Paclitaxel-Resistant Human Cervical-Adeno-Carcinoma Cells to Paclitaxel-And Enhances the Anticancer Effect of Paclitaxel. Genes (Basel). 2022 Jun 24;13(7):1142. doi: 10.3390/genes13071142. | Click |
